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https://github.com/TomGeorge1234/RatInABox

Software Python toolkit for modelling locomotion and neuronal activity in continuous environments. Used to model realistic rodent locomotion and generate synthetic electrophysiological data from spatially modulated cell types.

Proper citation: RatInABox (RRID:SCR_023682) Copy   

•   Source: SciCrunch Registry

https://github.com/MaSoMoTr/MaSoMoTr

Markerless video-based tool to simultaneously track two interacting mice of the same appearance in controlled settings for quantifying behaviors such as different types of sniffing, touching, and locomotion to improve tracking accuracy under these settings without increased human effort. It incorporates conventional handcrafted tracking and deep-learning-based techniques. The tool is trained on small number of manually annotated images from basic experimental setup and outputs body masks and coordinates of the snout and tail-base for each mouse.

Proper citation: Markerless Mouse Tracking for Social Experiments (RRID:SCR_025368) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/ort/

Open-source apparatus to enable continuous individual monitoring, training, and testing of rats without removing them from their social environment. This system utilizes RFID technology to track individual animals, minimizing human intervention and providing precise behavioral data.

Proper citation: One-rat Turnstile (RRID:SCR_025570) Copy   

•   Source: SciCrunch Registry

https://github.com/NeLy-EPFL/LiftPose3D

Software tool for transforming 2D poses to 3D coordinates on labaratory animals. Used for kinematic studies of laboratory animals. Tracking movements in three dimensions from behaving flies, mice, rats, and non-human primates.

Proper citation: LiftPose3D (RRID:SCR_023049) Copy   

•   Source: SciCrunch Registry

https://m3platform.weebly.com/

Software neuroscience laboratory environment for simultaneous neuronal imaging and behavioral monitoring. McGill-Mouse-Miniscope Touchscreen Behavior Platform. Standardized approach for high throughput imaging of neuronal dynamics during behavior.

Proper citation: M3 Platform (RRID:SCR_023425) Copy   

•   Source: SciCrunch Registry

https://github.com/WinterLab-Berlin/LabNet

Open source software for parallel control over multiple behavioral systems.C++ optimized control layer software to give access to Raspberry Pi connected hardware. Suitable for time critical operations, and to be simple to expand. Used for general automation in experimental laboratories with its control PC located at some distance.

Proper citation: LabNet (RRID:SCR_023712) Copy   

•   Source: SciCrunch Registry

https://github.com/BadenLab/LED-Zappelin

Open source LED controller for arbitrary spectrum visual stimulation and optogenetics during 2 photon imaging. Device that rapidly time interleaves stimulation and detection epochs during two photon imaging.

Proper citation: LED Zappelin’ (RRID:SCR_022560) Copy   

•   Source: SciCrunch Registry

https://github.com/BrettHewitt/ART

Software tool to automatically track rodent position and movement.Used to track head movements, body movements and also aspects of body size. It is able to identify certain behaviours from video footage too, such as rotations, moving forwards, interacting with objects and staying still.

Proper citation: Automated Rodent Tracker (RRID:SCR_021510) Copy   

•   Source: SciCrunch Registry

https://github.com/asoronow/belljar/tree/main

Software mouse brain histology tool for neuroscientists. Semiautomated registration and cell counting tool for mouse neurohistology analysis.

Proper citation: Bell Jar (RRID:SCR_026912) Copy   

•   Source: SciCrunch Registry

https://github.com/gchelini87/SEB3R

Software tool to automate and standardize ethologically driven observation of freely moving mice. Identifies different postures of mice and associates them with emotions, offering detailed analysis of their movements frame by frame. Used for tracking mouse body language and studying emotional behaviors.

Proper citation: SEB3R (RRID:SCR_025161) Copy   

•   Source: SciCrunch Registry

https://github.com/lnccbrown/HSSM

Software Python toolbox for fitting Hierarchical Sequential Sampling Models using Bayesian methods.

Proper citation: HSSM (RRID:SCR_026356) Copy   

•   Source: SciCrunch Registry

https://github.com/fchampalimaud/optical-lickometer

Low-cost open-source lickometer that combines restricted infrared beam defined by optical fibers, with poke design that allows easy access to the tongue while limiting access of other body parts and external light sources. This device also includes features for detecting nose pokes and presenting visual cues during behavioral tasks. Used to study lick microstructure in combination with other techniques, such as imaging of neural activity, in freely moving mice.

Proper citation: High-Precision Optical Fiber-Based Lickometer (RRID:SCR_026392) Copy   

•   Source: SciCrunch Registry

https://github.com/munoztd0/Mouthpiecegusto

3D printed pacifier shaped mouthpiece for fMRI compatible gustometers to deliver up to eight liquids during fMRI task. Can be utilized to study flavor, taste reactivity, reward or punishment with food, conditioning, and neurodegenerative conditions such as Alzheimers and Parkinsons, since taste and smell senses diminish early into disease acquisition.

Proper citation: 3DP Gustometer (RRID:SCR_025010) Copy   

•   Source: SciCrunch Registry

https://github.com/mcmelo22/Licktech/tree/main

Lickometer system based on open-source hardware platform with user-friendly interface software, capable of simultaneously receiving data from eight automated cages with two drinking bottles each. Device to acquire high-quality and detailed data. Adaptable to new types of sensors or other neuroscience tools capable of measuring brain activity simultaneously to the behavior.

Proper citation: Lickometer Box (RRID:SCR_025248) Copy   

•   Source: SciCrunch Registry

https://github.com/LurLab-UCI/HERBs

Open source hardware and software solution for flexible implementation of complex behaviors in head-fixed mice. Low cost and requires little to no programming experience. Allows neural activity to be seen during testing, which will show relations between neuronal activity and behavior during tasks such as alternative forced choice, GoNoGo, and sensory stimulus presentation.

Proper citation: HERBs (RRID:SCR_025381) Copy   

•   Source: SciCrunch Registry

https://github.com/Aharoni-Lab/Ephys-Miniscope

Miniaturized calcium imaging microscope with integrated dense electrode technology for synchronous acquisition of neural activity across distant regions of the brain. Device based off open-sourced UCLA Miniscope to synchronously measure single cell activity at or near spike-time resolution across distant brain regions in freely behaving mice. Used to perform calcium imaging, with dense electrode electrophysiological recording, allowing simultaneous recordings from two remote brain regions in freely behaving mouse.

Proper citation: E-Scope (RRID:SCR_025396) Copy   

•   Source: SciCrunch Registry

https://github.com/jfrie/FARESHARE

Open source device for fluid tracking in socially housed rats. Device uses RFID and custom hardware to individually measure and record each rat's fluid consumption and licking microstructure.

Proper citation: FARESHARE (RRID:SCR_025330) Copy   

•   Source: SciCrunch Registry

https://github.com/BerezhnoyD/Reaching_Task_VAI/

Open source hardware-software platform for analyzing reaching movement kinematics in mice. Used for studying fine motor skills in mice performing reach-to-grasp task. Behavioral platform uses readily available and 3D-printed components and was designed to be affordable and universally reproducible. Provides schematics, 3D models, code, and assembly instructions.

Proper citation: ReachOut (RRID:SCR_025502) Copy   

•   Source: SciCrunch Registry

https://github.com/3Dneuro/TD_Drive

Parametric, open-source implant for multi-area electrophysiological recordings in behaving and sleeping rats. 3D-printable implant for rats, capable of symmetric, bilateral wire electrode recordings, currently in up to six distributed brain areas simultaneously.

Proper citation: TD_Drive (RRID:SCR_025672) Copy   

•   Source: SciCrunch Registry

https://github.com/EstebanValverde/Holeboard-for-mice-behavior

Open-source holeboard for studying rodent behavior. Used in neuroscience for assessing exploration, anxiety, and spatial memory in rodents. The project provides a cost-effective solution, offering detailed instructions on sensor integration, circuit assembly, and Arduino programming for conducting experiments. Design files and other details are available on GitHub.

Proper citation: Holeboard (RRID:SCR_025988) Copy   

•   Source: SciCrunch Registry