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Repository for toxicogenomics data, including study design and timeline, clinical chemistry and histopathology findings and microarray and proteomics data. Data derived from studies of chemicals and of genetic alterations, and is compatible with clinical and environmental studies. Data relating to environmental health, pharmacology, and toxicology. It is not necessary to have microarray data, but study design and phenotypic anchoring data are required.CEBS contains raw microarray data collected in accordance with MIAME guidelines and provides tools for data selection, pre-processing and analysis resulting in annotated lists of genes of interest. Biomedical Investigation Database is another component of CEBS system. used to load and curate study data prior to export to CEBS, in addition to capturing and displaying novel data types such as PCR data, or additional fields of interest, including those defined by the HESI Toxicogenomics Committee. BID has been shared with Health Canada and the US Environmental Protection Agency.
Proper citation: Chemical Effects in Biological Systems (CEBS) (RRID:SCR_006778) Copy
http://purl.bioontology.org/ontology/WB-LS
A structured controlled vocabulary of the development of Caenorhabditis elegans.
Proper citation: C. elegans Development Vocabulary (RRID:SCR_006811) Copy
The BioBricks Foundation (BBF) is dedicated to advancing synthetic biology to benefit all people and the planet. To achieve this, we must make engineering biology easier, safer, equitable, and more open. We do this in the following ways: by ensuring that the fundamental building blocks of synthetic biology are freely available for open innovation; by creating community, common values and shared standards; and by promoting biotechnology for all constructive interests. We envision a world in which scientists and engineers work together using BioBric parts freely available standardized biological parts to create safe, ethical solutions to the problems facing humanity. We envision synthetic biology as a force for good in the world. We see a future in which architecture, medicine, environmental remediation, agriculture, and many other fields are using the technology of synthetic biology. Our supporters are many and include corporations, individuals, institutions, foundations, government, corporations, and others. Currently, the BBF''s key programs include: * BIOFAB * BioBrick Public Agreement * Technical Standards Framework * Conferences and Workshops * BBF Global Network * OpenWetWare
Proper citation: BioBricks Foundation (RRID:SCR_006779) Copy
http://thompsoncenter.missouri.edu/
The mission of the Thompson Center is to improve the lives of individuals and families affected by autism and neurodevelopmental disorders through world class programs that integrate research, clinical service delivery, education and public policy. The Thompson Center''s vision is to become a recognized national center of excellence that serves as a model of interdisciplinary practice, research and training in the field of autism and neurodevelopmental disorders. At the MU Thompson Center, education and training activities are a key part of our mission. Our goal is to teach others about the needs of persons with autism and other neurodevelopmental disorders and their families. In addition, we strive to help learners acquire skills needed to improve the outcomes of individuals with developmental differences. These skills include evidence-based assessment and intervention strategies, interdisciplinary approaches to service delivery, research methods, and policy development. The Thompson Center offers a range of health, educational and behavioral services in one location for individuals with autism and other developmental concerns. Professionals from different disciplines strive to deliver family-centered care that is comprehensive and coordinated. Autism recently has been recognized as a national public health concern, and federal research funding in this area has increased substantially. Faculty members engage in research that will lead to early identification, treatment and ultimately prevention of autism spectrum disorders (ASD). How findings may eventually translate into improved outcomes in clinical and community settings is a primary goal of our research.
Proper citation: Thompson Center for Autism and Neurodevelopmental Disorders (RRID:SCR_006812) Copy
http://www.ensemblgenomes.org/
Database portal offering integrated access to genome-scale data from non-vertebrate species of scientific interest, developed using the Ensembl genome annotation and visualization platform. Ensembl Genomes consists of five sub-portals (for bacteria, protists, fungi, plants and invertebrate metazoa) designed to complement the availability of vertebrate genomes in Ensembl. Many of the databases supporting the portal have been built in close collaboration with the scientific community - essential for maintaining the accuracy and usefulness of the resource. A common set of user interfaces (which include a graphical genome browser, FTP, BLAST search, a query optimized data warehouse, programmatic access, and a Perl API) is provided for all domains. Data types incorporated include annotation of (protein and non-protein coding) genes, cross references to external resources, and high throughput experimental data (e.g. data from large scale studies of gene expression and polymorphism visualized in their genomic context). Additionally, extensive comparative analysis has been performed, both within defined clades and across the wider taxonomy, and sequence alignments and gene trees resulting from this can be accessed through the site.
Proper citation: Ensembl Genomes (RRID:SCR_006773) Copy
Offers one and two week short courses in bioinformatics, genomics and proteomics in response to an identified need for a skilled bioinformatics workforce in Canada. For eight years, the series offered short courses in bioinformatics, genomics and proteomics in various cities across Canada. Taught by top faculty from Canada and the US, the courses offered small classes and hands-on instruction. The CBW initiated development of a new format and series of exciting workshops focusing on training the researchers of these advanced technologies on the latest approaches being used in computational biology to deal with the new data. Past workshop content is available under a Creative Commons License.
Proper citation: Canadian Bioinformatics Workshops (RRID:SCR_006774) Copy
http://sourceforge.net/projects/qudaich/
A software package for local sequence alignment for next-generation sequencing (NGS) data. It generates the pairwise local alignments between a query dataset against a database. The main design purpose of qudaich is to focus on datasets from next generation sequencing. These the datasets generally have hundreds of thousand sequences or more, and so, the input database should contain large number of sequences. Qudaich is flexible and its algorithmic structure imposes no restriction on the absolute limit of the acceptable read length, but the current version of qudaich allow read length <2000 bp. Qudaich can be used to align DNA, translated DNA and protein sequences.
Proper citation: Qudaich (RRID:SCR_006775) Copy
http://sourceforge.net/projects/aeo/
AEO represents the Adverse Event Ontology, a community-driven ontology developed to standardize and integrate data on biomedical adverse events (e.g., vaccine adverse events) and support computer-assisted reasoning. The AEO also can be found in BioPortal, http://bioportal.bioontology.org/ontologies/45534?p=terms
Proper citation: Adverse Event Ontology (RRID:SCR_006807) Copy
http://bmsr.usc.edu/software/adapt/
Software tool as plug-in developed for ImageJ/FIJI platform to automatically detect and analyse cell migration and morphodynamics. Provides whole cell analysis of multiple cells, while also returning data on individual membrane protrusion events.
Proper citation: ADAPT (RRID:SCR_006769) Copy
http://compbio.bccrc.ca/software/jointsnvmix/
Software that implements a probabilistic graphical model to analyze sequence data from tumor / normal pairs. The model draws statistical strength by analysing both genome jointly to more accurately classify germline and somatic mutations. It effectively reduces false positive somatic mutation predictions in tumour-normal pair sequencing data. It is highly recommended to post-process results with mutationSeq in order to filter technical artifacts.
Proper citation: JointSNVMix (RRID:SCR_006804) Copy
Information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) established to increase knowledge and understanding about diseases of the kidneys and urologic system among people with these conditions and their families, health care professionals, and the general public: online, in booklets and fact sheets, by email, and over the phone. To carry out this mission, NKUDIC works closely with a coordinating panel of representatives from Federal agencies; voluntary organizations on the national level; professional groups; and State health departments to identify and respond to informational needs about kidney and urologic diseases. NKUDIC provides the following informational products and services: * Response to inquiries about kidney and urologic diseases-ranging from information about available patient and professional education materials to statistical data. By phone (8:30 a.m. to 5 p.m. eastern time, M-F), fax, mail, and email. * Publications about specific kidney and urologic diseases, provided free of copyright, in varying reading levels. Available online or as booklets and brochures. (See our Publications Catalog.) NKUDIC also sends publications to health fairs and community events. Please contact us for more information. * Referrals to health professionals through the National Library of Medicine''''s MEDLINEplus includes a consumer-friendly listing of organizations that will assist you in your search for physicians and other health professionals. * Exhibits at professional meetings specific to kidney and urologic diseases, as well as cross-cutting professional meetings. NKUDIC exhibits at 11 professional meetings, each year, including Society of Urologic Nurses and Associates, American Urologic Association, American Society of Nephrology, National Kidney Foundation, Polycystic Kidney Disease Research Foundation, American Academy of Family Physicians, American Academy of Physician Assistants, American Nurses Association, and the National Conference for Nurse Practitioners.
Proper citation: National Kidney and Urologic Diseases Information Clearinghouse (RRID:SCR_006842) Copy
Funds innovative research and development in Washington state to promote life sciences competitiveness, enhance economic vitality, and improve health and health care. Its grantmaking opportunities are designed to leverage the state''s investment in research and development by achieving three goals: promoting health; making the life sciences sector more competitive; and strengthening Washington''s economy. LSDF currently offers two different types of granting mechanisms for both for-profit and non-profit organizations in Washington: * Proof of Concept grants to enhance the commercial viability of intellectual property developed by non-profit organizations or enhance the competitiveness of early-stage companies for private equity investment. (This grant mechanism combines the Commercialization and PreCede mechanisms offered in prior years.) * Opportunity grants to fund extraordinary research and development proposals having the ability to significantly leverage LSDF dollars against those from other sources.
Proper citation: Life Sciences Discovery Fund (RRID:SCR_006845) Copy
A Graphical User Interface for NEURON simulator environment with 3D capabilities. Neuronvisio makes easy to select and investigate sections'''' properties and it offers easy integration with matplotlib for plotting the results. The geometry can be saved using NeuroML and the computational results in a customized and extensible HDF5 format; the results can then be reload in the software and analyzed in a later stage, without re-running the simulation. Featuring 3D visualization of the model with the possibility to change it runtime; creation of vectors to record any variables present in the section; pylab integration to plot directly the result of the simulation; exploration of the timecourse of any variable among time using a color coded scale; saving the results simulation for later analysis; automatic download and running of models in ModelDB.
Proper citation: NeuronVisio (RRID:SCR_006839) Copy
http://purl.bioontology.org/ontology/WB-BT
A structured controlled vocabulary of the anatomy of Caenorhabditis elegans.
Proper citation: C. elegans Gross Anatomy Vocabulary (RRID:SCR_006835) Copy
http://dally.nimh.nih.gov/index.html
A program developed by the NIMH Laboratory of Neuropsychology for data acquisition and experimental control of neurophysiological experiments. The purpose of this website is to make it easier to access new versions of NIMH CORTEX and its supporting documents. Ultimately, it is also hoped that these pages will make it easier for users to report bugs, request enhancements, and obtain help. Download the latest version and unzip it into a new sub-directory. Then read the on-line documentation. For the new user, the User''s Manuals are invaluable in specifying system requirements and giving an overview of the features and necessary hardware. The Function reference goes into more detail about how to write experiments using NIMH CORTEX. The Demos reference is a good place for new and experienced users to start to get an idea of what NIMH CORTEX can do these days.
Proper citation: NIMH CORTEX (RRID:SCR_006837) Copy
http://sourceforge.net/projects/gbsbarcode/
PERL script used to split barcode of Illumina sequencing data created by GBS protocol (www.maizegenetics.net). The barcode has variable size. Paired-end reads are supported.
Proper citation: GBS barcode splitter (RRID:SCR_006799) Copy
canSAR is an integrated database that brings together biological, chemical, pharmacological (and eventually clinical) data. Its goal is to integrate this data and make it accessible to cancer research scientists from multiple disciplines, in order to help with hypothesis generation in cancer research and support translational research. This cancer research and drug discovery resource was developed to utilize the growing publicly available biological annotation, chemical screening, RNA interference screening, expression, amplification and 3D structural data. Scientists can, in a single place, rapidly identify biological annotation of a target, its structural characterization, expression levels and protein interaction data, as well as suitable cell lines for experiments, potential tool compounds and similarity to known drug targets. canSAR has, from the outset, been completely use-case driven which has dramatically influenced the design of the back-end and the functionality provided through the interfaces. The Web interface provides flexible, multipoint entry into canSAR. This allows easy access to the multidisciplinary data within, including target and compound synopses, bioactivity views and expert tools for chemogenomic, expression and protein interaction network data.
Proper citation: canSAR (RRID:SCR_006794) Copy
http://purl.bioontology.org/ontology/IDOBRU
A biomedical ontology in the domain of zoonotic disease brucellosis that is caused by Brucella, a facultative intracellular baterium.
Proper citation: Brucellosis Ontology (RRID:SCR_006795) Copy
https://itunes.apple.com/gb/app/neuropub-visualizer/id405721542?mt=8
A NIfTI visualizer for statistical brain images (fMRI, VBM, etc) the iPad. The visualizer displays these images as overlay on the MNI standard brain. You can use it to store all your statistical images from your fMRI / VBM / TBSS studies and visualise them in 2D and 3D. Use NeuroPub as a library for your statistical images. It's the perfect app to bring to meetings, conferences, etc, and show your latest results.
Proper citation: NeuroPub Visualizer (RRID:SCR_006797) Copy
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