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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_0518
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: KCB Cat# KCB 2010008YJ, RRID:CVCL_0518 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: KCB Cat# KCB 92018YJ, RRID:CVCL_0549 Copy
https://web.expasy.org/cellosaurus/CVCL_0032
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Virology: Contains a complete HPV16 genome with a disruption of the E2 region and a small deletion (PubMed=24201445)., Population: Japanese., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: KCB Cat# KCB 2013026YJ, RRID:CVCL_0032 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0059
Organism: Chlorocebus sabaeus (Green monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: KCB Cat# KCB 92017YJ, RRID:CVCL_0059 Copy
https://web.expasy.org/cellosaurus/CVCL_A9JM
Organism: Bubalus bubalis x Bubalus carabanensis (Hybrid buffalo)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 2010218ZJ, RRID:CVCL_A9JM Copy
https://web.expasy.org/cellosaurus/CVCL_XZ97
Organism: Capra hircus aegagrus (Wild goat)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 90015ZJ, RRID:CVCL_XZ97 Copy
https://web.expasy.org/cellosaurus/CVCL_A9FV
Organism: Sciurus vulgaris (Eurasian red squirrel)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 2011024KZJ, RRID:CVCL_A9FV Copy
https://web.expasy.org/cellosaurus/CVCL_A9FU
Organism: Sciurus vulgaris (Eurasian red squirrel)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 2011024HZJ, RRID:CVCL_A9FU Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_6851
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: Formerly the CCRID database had 3 entries describing this cell line (3111C0001CCC000296, 3131C0001000700077, 3142C0001000000067). They were one of the sources for the STR profile of this entry., Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28851942). Originally thought to originate from a female patient with a tongue squamous cell carcinoma..
Proper citation: KCB Cat# KCB 93034YJ, RRID:CVCL_6851 Copy
Discontinued Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0579
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Anecdotal: Have been flown in space on Skylab-3 to study growth in microgravity (PubMed=352912)., Anecdotal: Leonard Hayflick when numbering diploid cell strains 'jumped' directly from WI-27 (which failed) to WI-38 (CelloPub=CLPUB00391)., Senescence: Life expectancy of 50 +- 10 population doublings. Senesces at 38 PDL (PubMed=17395773)., Characteristics: Used in many context such as senescence and aging studies., Biotechnology: Was used in the early 1970's for the production of the Human Diploid Cell Vaccine (HDCV) vaccine against rabies by Institut Merieux., Biotechnology: Used for the production of live oral adenovirus type 4 and type 7 vaccine used by the US military. Produced first by Wyeth Laboratories from 1971 to 1999 and from 2011 onward by Barr Pharmaceuticals., Biotechnology: Used for the production of RA27/3 - the first rubella virus vaccine., Population: Caucasian; Swedish., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut).
Proper citation: KCB Cat# KCB 200556YJ, RRID:CVCL_0579 Copy
https://web.expasy.org/cellosaurus/CVCL_XB58
Organism: Mus musculus (Mouse)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 85024ZJ, RRID:CVCL_XB58 Copy
https://web.expasy.org/cellosaurus/CVCL_A9HC
Organism: Tupaia chinensis (Chinese tree shrew)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 2010007SZJ, RRID:CVCL_A9HC Copy
https://web.expasy.org/cellosaurus/CVCL_A9HE
Organism: Tupaia chinensis (Chinese tree shrew)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 200305KZJ, RRID:CVCL_A9HE Copy
https://web.expasy.org/cellosaurus/CVCL_A9HB
Organism: Tupaia chinensis (Chinese tree shrew)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 2010007HZJ, RRID:CVCL_A9HB Copy
https://web.expasy.org/cellosaurus/CVCL_3804
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: KCB Cat# KCB 2019018YJ, RRID:CVCL_3804 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0421
Organism: Bos taurus (Bovine)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Not susceptible to infection by wild-type and vaccinal strains of myxoma virus (MYXV) (PubMed=17900332)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: KCB Cat# KCB 90031YJ, RRID:CVCL_0421 Copy
https://web.expasy.org/cellosaurus/CVCL_2111
Organism: Mus musculus (Mouse)
Disease: Mouse erythroid leukemia
Category: Cancer cell line
Comments: Part of: ENCODE project mouse cell lines.
Proper citation: KCB Cat# KCB 200855YJ, RRID:CVCL_2111 Copy
https://web.expasy.org/cellosaurus/CVCL_5J48
Organism: Mus musculus (Mouse)
Disease: Mouse gastric carcinoma
Category: Cancer cell line
Comments:
Proper citation: KCB Cat# KCB 92020YJ, RRID:CVCL_5J48 Copy
https://web.expasy.org/cellosaurus/CVCL_2153
Organism: Mus musculus (Mouse)
Disease: Mouse teratocarcinoma
Category: Cancer cell line
Comments: Caution: There seem to be 3 distinct cell lines which were assigned NCBI_Iran catalog number C422.
Proper citation: KCB Cat# KCB 200844YJ, RRID:CVCL_2153 Copy
https://web.expasy.org/cellosaurus/CVCL_BS84
Organism: Vulpes vulpes (Red fox)
Disease:
Category: Finite cell line
Comments:
Proper citation: KCB Cat# KCB 88011KZJ, RRID:CVCL_BS84 Copy
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