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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_0142
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 305172, RRID:CVCL_0142 Copy
https://web.expasy.org/cellosaurus/CVCL_U287
Organism: Homo sapiens (Human)
Disease: Ovarian carcinoma
Category: Cancer cell line
Proper citation: CLS Cat# 305144, RRID:CVCL_U287 Copy
https://web.expasy.org/cellosaurus/CVCL_0605
Organism: Mus musculus (Mouse)
Disease: Mouse insulinoma
Category: Transformed cell line
Comments: Characteristics: Secretes insulin in response to glucose challenge. But this phenotype is unstable., Group: Patented cell line.
Proper citation: CLS Cat# 305181, RRID:CVCL_0605 Copy
Discontinued Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_1953
Organism: Saguinus oedipus (Cotton-top tamarin)
Category: Transformed cell line
Comments: Virology: This cell line sheds the Epstein-Barr virus (EBV) strain B95-8 and is often used to transform human or other primates B lymphocytes., Characteristics: Was established by exposure to extracts of the 883L cell line (Cellosaurus=CVCL_6A87)., Group: Non-human primate cell line.
Proper citation: CLS Cat# 305152, RRID:CVCL_1953 Copy
https://web.expasy.org/cellosaurus/CVCL_0159
Organism: Mus musculus (Mouse)
Disease: Mouse melanoma
Category: Cancer cell line
Comments: Characteristics: Has a high metastatic potential., Characteristics: Obtained from the pulmonary melanoma module of the 10th serial passage of the B16-F0 parent cell line in C57BL/6 mice.
Proper citation: CLS Cat# 305157, RRID:CVCL_0159 Copy
https://web.expasy.org/cellosaurus/CVCL_0223
Organism: Chlorocebus aethiops (Green monkey)
Category: Transformed cell line
Comments: Group: Non-human primate cell line.
Proper citation: CLS Cat# 305005, RRID:CVCL_0223 Copy
https://web.expasy.org/cellosaurus/CVCL_7213
Organism: Rattus norvegicus (Rat)
Category: Spontaneously immortalized cell line
Proper citation: CLS Cat# 305206, RRID:CVCL_7213 Copy
https://web.expasy.org/cellosaurus/CVCL_0125
Organism: Mus musculus (Mouse)
Disease: Malignant neoplasms of the mouse mammary gland
Category: Cancer cell line
Comments: Characteristics: Widely used model in cancer research due to its high similarity to human breast cancer. The tumor growth and metastatic spread of 4T1 cells closely mimic the behavior of human breast cancer. The 4T1 cell line is considered an animal model for stage IV human breast cancer, as it is able to spontaneously metastasize in both post-operative and non-surgical models (CLS=300300)., Characteristics: Metastatic.
Proper citation: CLS Cat# 300300, RRID:CVCL_0125 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_U957
Organism: Homo sapiens (Human)
Disease: Breast adenocarcinoma
Category: Cancer cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Problematic cell line: Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile)..
Proper citation: CLS Cat# 300280, RRID:CVCL_U957 Copy
https://web.expasy.org/cellosaurus/CVCL_C7GY
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Population: Caucasian., From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Proper citation: CLS Cat# 302107, RRID:CVCL_C7GY Copy
https://web.expasy.org/cellosaurus/CVCL_0209
Organism: Homo sapiens (Human)
Disease: Adult acute myeloid leukemia
Category: Transformed cell line
Comments: Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300262, RRID:CVCL_0209 Copy
https://web.expasy.org/cellosaurus/CVCL_2344
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Senescence: Senesces at ~36 PDL (ATCC=CRL-2122)., Population: Caucasian.
Proper citation: CLS Cat# 300642, RRID:CVCL_2344 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0255
Organism: Mus musculus (Mouse)
Disease: Mouse precursor T cell lymphoblastic lymphoma/leukemia
Category: Cancer cell line
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Proper citation: CLS Cat# 300653, RRID:CVCL_0255 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0307
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: CLS Cat# 304064, RRID:CVCL_0307 Copy
https://web.expasy.org/cellosaurus/CVCL_II76
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Virology: Susceptible to infection by Chikungunya virus. Supports viral replication with no signifcant loss in cell viability until 72 hours post infection (PubMed=35352315).
Proper citation: CLS Cat# 300102, RRID:CVCL_II76 Copy
https://web.expasy.org/cellosaurus/CVCL_E919
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Part of: International Histocompatibility Workshop cell lines.
Proper citation: CLS Cat# 302139, RRID:CVCL_E919 Copy
Discontinued Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0579
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Anecdotal: Have been flown in space on Skylab-3 to study growth in microgravity (PubMed=352912)., Anecdotal: Leonard Hayflick when numbering diploid cell strains 'jumped' directly from WI-27 (which failed) to WI-38 (CelloPub=CLPUB00391)., Senescence: Life expectancy of 50 +- 10 population doublings. Senesces at 38 PDL (PubMed=17395773)., Characteristics: Used in many context such as senescence and aging studies., Biotechnology: Was used in the early 1970's for the production of the Human Diploid Cell Vaccine (HDCV) vaccine against rabies by Institut Merieux., Biotechnology: Used for the production of live oral adenovirus type 4 and type 7 vaccine used by the US military. Produced first by Wyeth Laboratories from 1971 to 1999 and from 2011 onward by Barr Pharmaceuticals., Biotechnology: Used for the production of RA27/3 - the first rubella virus vaccine., Population: Caucasian; Swedish., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut).
Proper citation: CLS Cat# 300428, RRID:CVCL_0579 Copy
https://web.expasy.org/cellosaurus/CVCL_0123
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma.
Proper citation: CLS Cat# 400107, RRID:CVCL_0123 Copy
https://web.expasy.org/cellosaurus/CVCL_4358
Organism: Mus musculus (Mouse)
Disease: Malignant tumors of the mouse pulmonary system
Category: Cancer cell line
Comments: Caution: Could be identical to 3LL (Cellosaurus=CVCL_5653).
Proper citation: CLS Cat# 305311, RRID:CVCL_4358 Copy
https://web.expasy.org/cellosaurus/CVCL_UJ16
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 305258, RRID:CVCL_UJ16 Copy
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