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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=150519901
Proper Citation: RRID:RGD_150519901
Description: Rattus norvegicus with name F344-Prkar1bem2Tua from RGD.
Species: Rattus norvegicus
Notes: CRISPR/Cas9 system containing guide RNAs targeting exon 2 and intron 2 were introduced into the F344/Stm embryos using a super electroporator NEPA 2. This mutant strain F344-Prkar1bem2Tua carried a 13-bp frameshift deletion in exon2 creating a premature stop codon in the Prkar1b transcripts. Expression levels of Prkar1b transcripts and protein are significantly decreased in the mutants.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
