URL: http://cng.gmu.edu:8080/Lm
Proper Citation: L-Measure (RRID:SCR_003487)
Description: A freely available software tool available for the Windows and Linux platform, as well as the Online version Applet, for the analysis, comparison and search of digital reconstructions of neuronal morphologies. For the quantitative characterization of neuronal morphology, LM computes a large number of neuroanatomical parameters from 3D digital reconstruction files starting from and combining a set of core metrics. After more than six years of development and use in the neuroscience community, LM enables the execution of commonly adopted analyses as well as of more advanced functions, including: (i) extraction of basic morphological parameters, (ii) computation of frequency distributions, (iii) measurements from user-specified subregions of the neuronal arbors, (iv) statistical comparison between two groups of cells and (v) filtered selections and searches from collections of neurons based on any Boolean combination of the available morphometric measures. These functionalities are easily accessed and deployed through a user-friendly graphical interface and typically execute within few minutes on a set of 20 neurons. The tool is available for either online use on any Java-enabled browser and platform or may be downloaded for local execution under Windows and Linux.
Abbreviations: LM
Resource Type: service resource, data processing software, image processing software, image analysis software, software resource, software application
Defining Citation: PMID:18451794
Keywords: neuronal morphology, neuroinformatics, branching analysis, digital reconstruction, analysis, comparison, bio.tools
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