Searching the Resource Information Network

Our searching services are busy right now. Please try again later

  • Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

Publication

MARCH1 negatively regulates TBK1-mTOR signaling pathway by ubiquitinating TBK1.

Xiao Li | Kai Cheng | Meng-Di Shang | Yong Yang | Bin Hu | Xi Wang | Xiao-Dan Wei | Yan-Chun Han | Xiao-Gang Zhang | Meng-Hua Dong | Zhen-Lin Yang | Jiu-Qiang Wang
BMC cancer | 2024

TBK1 positively regulates the growth factor-mediated mTOR signaling pathway by phosphorylating mTOR. However, it remains unclear how the TBK1-mTOR signaling pathway is regulated. Considering that STING not only interacts with TBK1 but also with MARCH1, we speculated that MARCH1 might regulate the mTOR signaling pathway by targeting TBK1. The aim of this study was to determine whether MARCH1 regulates the mTOR signaling pathway by targeting TBK1.

Pubmed ID: 39061024

Research resources used in this publication

None found

Additional research tools detected in this publication

Antibodies used in this publication

None found

Associated grants

  • Agency: Natural Science Foundation of Shandong Province,
    Id: ZR2023QH126
  • Agency: Natural Science Foundation of Shandong Province,
    Id: ZR2023QC303
  • Agency: Binzhou Medical University,
    Id: 50012304623
  • Agency: Binzhou Medical University,
    Id: 50012304496

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.

Millipore (tool)

RRID:SCR_008983

An Antibody supplier

View all literature mentions

Proteintech Group (tool)

RRID:SCR_008986

Proteintech Europe Ltd is an ISO 9001:2008 certified company

View all literature mentions

About

The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

Recent News Entries

Contact Us

Department of Neurosciences, School of Medicine

University of California, San Diego





About SciCrunch | Privacy Policy | Terms of Service

SciCrunch