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The regulatory effect of TiO2 nanotubes loaded with graphene oxide on macrophage polarization in an inflammatory environment.

Xu Cao | Bin Luo | Yanting Mu | Caiyun Wang | Ran Lu | Yao Yao | Su Chen
BMC oral health | 2024

Excessive inflammation is a major cause of implant failure. The surface morphology, hydrophilicity, and loading of biomaterials are major properties modulating anti-inflammatory macrophage activation. This paper investigates the regulatory effects of modifying the surface of Titanium dioxide nanotubes (TNTs) with graphene oxide (GO) on the polarization of mouse monocyte macrophages (RAW264.7).

Pubmed ID: 39033148

Research resources used in this publication

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Associated grants

  • Agency: Beijing Stomatological Hospital Capital Medical University Young Scientist Program,
    Id: YSP202316
  • Agency: National Natural Science Foundation of China,
    Id: 81873722
  • Agency: the Beijing Hospital Authority Talent Training Plan,
    Id: DFL 20221301

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Thermo Fisher Scientific (tool)

RRID:SCR_008452

Commercial vendor and service provider of laboratory reagents and antibodies. Supplier of scientific instrumentation, reagents and consumables, and software services.

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htseq-count (tool)

RRID:SCR_011867

Script distributed with the HT-Seq Python framework for processing RNA-seq or DNA-seq data.

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KEGG (tool)

RRID:SCR_012773

Integrated database resource consisting of 16 main databases, broadly categorized into systems information, genomic information, and chemical information. In particular, gene catalogs in completely sequenced genomes are linked to higher-level systemic functions of cell, organism, and ecosystem. Analysis tools are also available. KEGG may be used as reference knowledge base for biological interpretation of large-scale datasets generated by sequencing and other high-throughput experimental technologies.

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