Searching the Resource Information Network

Our searching services are busy right now. Please try again later

  • Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

Publication

Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion.

Junnan Liu | Xue Wang | Wencheng Jiang | Anca Azoitei | Tim Eiseler | Markus Eckstein | Arndt Hartmann | Stephan Stilgenbauer | Mohamed Elati | Meike Hohwieler | Alexander Kleger | Axel John | Felix Wezel | Friedemann Zengerling | Christian Bolenz | Cagatay Günes
Cellular & molecular biology letters | 2024

We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor formation in xenograft models. The molecular mechanisms by which loss of GJB3 leads to aneuploidy and cancer initiation and progression remain unsolved.

Pubmed ID: 38956497

Research resources used in this publication

Additional research tools detected in this publication

Antibodies used in this publication

None found

Associated grants

  • Agency: Deutsche Forschungsgemeinschaft,
    Id: GU569/6-1
  • Agency: Deutsche Forschungsgemeinschaft,
    Id: EI792/7-1
  • Agency: Wilhelm Sander-Stiftung,
    Id: 2019.038.1

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.

C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

View all literature mentions

pLV-MPAct-mCit-IRES-Neo (plasmid)

RRID:Addgene_155230

View all literature mentions

About

The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

Recent News Entries

Contact Us

Department of Neurosciences, School of Medicine

University of California, San Diego





About SciCrunch | Privacy Policy | Terms of Service

SciCrunch