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ANGPTL7 and Its Role in IOP and Glaucoma.

Suzette Farber-Katz Brown | Hien Nguyen | Philip Mzyk | Michael L De Ieso | Andrea M Unser | Ian Brown | Pujhitha Ramesh | Hira Afzaal | Feryan Ahmed | Karen Y Torrejon | Alan Nhan | Dalton Markrush | Tom Daly | Ellie Knecht | William McConaughy | Sara Halmos | Zhiquan Lucy Liu | Rachel Rennard | Andrew Peterson | W Daniel Stamer
Investigative ophthalmology & visual science | 2024

Loss-of-function variants in the ANGPTL7 gene are associated with protection from glaucoma and reduced intraocular pressure (IOP). We investigated the role of ANGPTL7 in IOP homeostasis and its potential as a target for glaucoma therapeutics.

Pubmed ID: 38497513

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: NEI NIH HHS, United States
    Id: P30 EY005722
  • Agency: NEI NIH HHS, United States
    Id: R01 EY022359

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RayBiotech (tool)

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Thermo Fisher Scientific (tool)

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QIAGEN (tool)

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A commercial organization which provides assay technologies to isolate DNA, RNA, and proteins from any biological sample. Assay technologies are then used to make specific target biomolecules, such as the DNA of a specific virus, visible for subsequent analysis.

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Sigma-Aldrich (tool)

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American chemical, life science and biotechnology company owned by Merck KGaA. Merger of Sigma Chemical Company and Aldrich Chemical Company. Provides organic and inorganic chemicals, building blocks, reagents, advanced materials and stable isotopes for chemical synthesis, medicinal chemistry and materials science, antibiotics, buffers, carbohydrates, enzymes, forensic tools, hematology and histology, nucleotides, proteins, peptides, amino acids and their derivatives.

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