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Nobiletin alleviates atherosclerosis by inhibiting lipid uptake via the PPARG/CD36 pathway.

Heng Wang | Qinqin Tian | Ruijing Zhang | Qiujing Du | Jie Hu | Tingting Gao | Siqi Gao | Keyi Fan | Xing Cheng | Sheng Yan | Guoping Zheng | Honglin Dong
Lipids in health and disease | 2024

Atherosclerosis (AS) is a persistent inflammatory condition triggered and exacerbated by several factors including lipid accumulation, endothelial dysfunction and macrophages infiltration. Nobiletin (NOB) has been reported to alleviate atherosclerosis; however, the underlying mechanism remains incompletely understood.

Pubmed ID: 38468335

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Associated grants

  • Agency: Shanxi Leading Talent Team Building Program,
    Id: 202204051002010
  • Agency: Shanxi Provincial Science and Technology Department Centralized Guided Local Projects,
    Id: YDZJSX2021C026
  • Agency: National Natural Science Foundation of China,
    Id: 81870354
  • Agency: Youth Fund of the Second Hospital of Shanxi Medical University,
    Id: 202002-5

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B6.129P2-Apoetm1Unc/J (tool)

RRID:IMSR_JAX:002052

Mus musculus with name B6.129P2-Apoetm1Unc/J from IMSR.

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