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Routine evaluation of HBV-specific T cell reactivity in chronic hepatitis B using a broad-spectrum T-cell epitope peptide library and ELISpot assay.

Yandan Wu | Xiaotao Liu | Yuan Mao | Ruixue Ji | Lingzhi Xia | Zining Zhou | Yan Ding | Pinqing Li | Yu Zhao | Min Peng | Jie Qiu | Chuanlai Shen
Journal of translational medicine | 2024

The clinical routine test of HBV-specific T cell reactivity is still limited due to the high polymorphisms of human leukocyte antigens (HLA) in patient cohort and the lack of universal detection kit, thus the clinical implication remains disputed.

Pubmed ID: 38468254

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Associated grants

  • Agency: Jiangsu Provincial Science and Technology Fund of China,
    Id: BE2017714
  • Agency: Nanjing Municipal Hygiene and Health Fund of Jiangsu Province,
    Id: zkx18043
  • Agency: Jiangsu Provincial Hygiene and Health Fund,
    Id: M2020088
  • Agency: National Natural Science Foundation of China,
    Id: 82272402

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