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A fruit extract of Styphnolobium japonicum (L.) counteracts oxidative stress and mediates neuroprotection in Caenorhabditis elegans.

Sara Thabit | Heba Handoussa | Nesrine S ElSayed | Hans-Georg Breitinger | Ulrike Breitinger | Michael Wink
BMC complementary medicine and therapies | 2023

Despite its widespread uses in Chinese and European medicine, Styphnolobium japonicum (Chinese scholar tree, formerly Sophora japonicum) has not been extensively investigated for its potential to protect against neurodegenerative processes and to promote resistance to oxidative stress. In this study, we evaluated the neuroprotective activities of a hydroalcoholic extract from Chinese scholar tree fruits that could be possibly linked to its antioxidant properties using Caenorhabditis elegans as a well-established in vivo model.

Pubmed ID: 37726773

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Associated grants

  • Agency: Science, Technology &. Innovation Funding Authority (STDF),
    Id: 43260

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