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Publication

Relaxin-2 Prevents Erectile Dysfunction by Cavernous Nerve, Endothelial and Histopathological Protection Effects in Rats with Bilateral Cavernous Nerve Injury.

Kang Liu | Taotao Sun | Wenchao Xu | Jingyu Song | Yinwei Chen | Yajun Ruan | Hao Li | Kai Cui | Yan Zhang | Yuhong Feng | Jiancheng Pan | Enli Liang | Zhongcheng Xin | Tao Wang | Shaogang Wang | Jihong Liu | Yang Luan
The world journal of men's health | 2023

Cavernous nerve injury induced erectile dysfunction (ED) is a refractory complication with high incidence in person under radical prostatectomy. Studies have shown that relaxin-2 (RLX-2) plays a vital role of endothelial protection, vasodilation, anti-fibrosis and neuroprotection in a variety of diseases. However, whether penile cavernous erection can benefit from RLX-2 remains unknown. The purpose of the experiment was to explore the effects of RLX-2 on ED in the rat suffering with bilateral cavernous nerve injury (BCNI).

Pubmed ID: 36047071

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Associated grants

  • Agency: National Natural Science Foundation of China, China
    Id: 81801439
  • Agency: National Natural Science Foundation of China, China
    Id: 81873831

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