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Nucleophosmin3 carried by small extracellular vesicles contribute to white adipose tissue browning.

Yan Zhang | Mei Yu | Jia Dong | Yue Wu | Weidong Tian
Journal of nanobiotechnology | 2022

Browning of white adipose tissue (WAT) is a particularly appealing target for therapeutics in the treatment of obesity and related metabolic diseases. Although small extracellular vesicles (sEVs) released from adipose tissue (sEVs-AT) have emerged as novel player that regulate systemic metabolism by connecting different organs, the role of specific contents in sEVs-AT played in WAT browning has not been clarified.

Pubmed ID: 35346213

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Associated grants

  • Agency: Key Technologies Research and Development Program,
    Id: 2017YFA0104800
  • Agency: Department of Science and Technology of Sichuan Province,
    Id: 2019YFS0312

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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3T3-L1 (tool)

RRID:CVCL_0123

Cell line 3T3-L1 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)

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