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Maternal exposure to CeO2NPs derails placental development through trophoblast dysfunction mediated by excessive autophagy activation.

Zhuxiu Chen | Yanqing Geng | Rufei Gao | Hangtian Zhong | Jun Chen | Xinyi Mu | Xuemei Chen | Yan Zhang | Fangfang Li | Junlin He
Journal of nanobiotechnology | 2022

The increasing use of cerium dioxide nanoparticles (CeO2NPs) in biomedical field has attracted substantial attention about their potential risks to human health. Recent studies have shown that nanoparticles can induce placental dysfunction and even fetal abortion, but a more detailed mechanism of nanoparticles affecting placental development remains elusive.

Pubmed ID: 35292031

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