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Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice.

Dániel Kucsera | Viktória E Tóth | Dorottya Gergő | Imre Vörös | Zsófia Onódi | Anikó Görbe | Péter Ferdinandy | Zoltán V Varga
Frontiers in physiology | 2021

The prevalence of non-alcoholic steatohepatitis (NASH) rapidly increases with associated metabolic disorders such as dyslipidemia; therefore, NASH is now considered an independent risk factor of cardiovascular diseases. NASH displays sex-linked epidemiological, phenotypical, and molecular differences; however, little is known about the background of these sex-specific differences on the molecular level.

Pubmed ID: 33692700

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Cell Signaling Technology (tool)

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