Searching the Resource Information Network

Our searching services are busy right now. Please try again later

  • Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele.

Jinghui Guo | Weihao Di | Wenxin Zhang | Qiuting Dai | Jian Zhao | Yulei Deng | Ying Wang
Stem cell research | 2021

Induced pluripotent stem cells play vitally essential roles in regenerative medicines for disease modeling and drug screening. Here, we successfully generated an iPSC line from PBMC of a 60-year-old female with mild cognitive impairment in an APOE 4/4 background to better understand studies relating to MCI and other cognitive diseases. In the newly-developed hiPSC line SIAISi009-A, all pluripotent markers were well expressed. Moreover, cells displayed a normal karyotype and have differentiation potential proven by in vitro trilineage differentiation method.

Pubmed ID: 33524675

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.


SnapGene (tool)

RRID:SCR_015052

Molecular biology software for visualizing and documenting gene constructs for InFusion cloning, Gibson assembly, restriction cloning, PCR, and mutagenesis.

View all literature mentions

GeneMapper (tool)

RRID:SCR_014290

Genotyping software package that provides DNA sizing and quality allele calls for all Applied Biosystems electrophoresis-based genotyping systems. GeneMapper specializes in multiapplication functionality, including amplified fragment length polymorphism, loss of heterozygosity, microsatellite, and SNP genotyping analysis. The software provides remote auto-analysis and command line operation, and allows for multiuser, client-server deployment.

View all literature mentions

Human Otx2 Affinity Purified Polyclonal Ab (antibody)

RRID:AB_2157172

This polyclonal targets Human Otx2 Affinity Purified Ab

View all literature mentions

TRA-1-81 (TRA-1-81) Mouse mAb (antibody)

RRID:AB_2119060

This monoclonal targets TRA-1-81 (TRA-1-81) Mouse mAb

View all literature mentions

Oct3/4 Antibody (C-10) (antibody)

RRID:AB_628051

This monoclonal targets Oct-3/4

View all literature mentions

SSEA4 antibody [MC813] - Embryonic Stem Cell Marker (antibody)

RRID:AB_778073

This monoclonal targets SSEA4 antibody [MC813] - Embryonic Stem Cell Marker

View all literature mentions

Sox17 (D1T8M) Rabbit mAb #81778 (antibody)

RRID:AB_2650582

This monoclonal targets residues surrounding Pro272 of human Sox17 protein

View all literature mentions

Brachyury (D2Z3J) Rabbit mAb (antibody)

RRID:AB_2799983

This monoclonal targets Brachyury

View all literature mentions

Sox2 (D6D9) XP Rabbit mAb (antibody)

RRID:AB_2195767

This monoclonal targets Sox2

View all literature mentions