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Decreased expression of endothelial cell specific molecule-1 in lung tissue in emphysematous mice and stable COPD patients.

Yan Zhang | Ping Chen | Shan Cai | Jinhua Li | Yan Chen
Iranian journal of basic medical sciences | 2020

Apoptosis of pulmonary alveolar septal cells is a pathogenesis characteristic of chronic obstructive pulmonary disease (COPD). Endothelial cell specific molecule-1 (ESM-1) plays an important role in apoptosis of cells. Here, we aimed to determine whether ESM-1 can involve in cell apoptosis in emphysematous mice and stable COPD patients. The sample size of patients was small, so two separate models were studied.

Pubmed ID: 33489036

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