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Silencing PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced neuronal apoptosis via activation of PI3K/AKT signaling in PC12 cells.

Shanshan Qiao | Dexin Yang | Xiaofeng Li | Weiping Li | Yuan Zhang | Wenlan Liu
Life sciences | 2021

Neuronal apoptosis acts as the pivotal pathogenesis of cerebral ischemia/reperfusion (I/R) injury after ischemic stroke. PAQR3 (progestin and adipoQ receptor family member 3) is a crucial player who participates in the regulation of cell death. We aim to explore the specific function and the underlying mechanism of PAQR3 in cerebral I/R induced neuronal injury.

Pubmed ID: 33249098

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This is a list of tools and resources that we have found mentioned in this publication.


PC12 (tool)

RRID:CVCL_0481

Cell line PC12 is a Cancer cell line with a species of origin Rattus norvegicus

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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