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MAPK pathway and SIRT1 are involved in the down-regulation of secreted osteopontin expression by genistein in metastatic cancer cells.

Kitboklang Khongsti | Kuheli Biswas Das | Bidyadhar Das
Life sciences | 2021

The regulation of secreted osteopontin (OPN) expression by genistein and its functional sequel in the metastatic cancer cells (MDA-MB-435 and MDA-MB-231) was ascertained.

Pubmed ID: 33249095

Antibodies used in this publication

None found

Associated grants

None

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This is a list of tools and resources that we have found mentioned in this publication.


The Li Lab at UCSF (tool)

RRID:SCR_010269

Laboratory portal that houses the following databases. MethPrimer is a program for designing bisulfite-conversion-based Methylation PCR Primers. Currently, it can design primers for two types of bisulfite PCR: 1) Methylation-Specific PCR (MSP) and 2) Bisulfite-Sequencing PCR (BSP) or Bisulfite-Restriction PCR. CpG Island Prediction MethPrimer can also analyze input sequences for the existence of CpG islands. Human Prostate Gene Database (PGDB) is a curated and integrated database of human genes related to the prostate and prostatic diseases. Human Kidney Gene Database (KGDB) is a curated and integrated database of human genes related to the kidney and renal diseases. The Li Lab is interested in understanding how small RNA regulates gene expression at the transcriptional level by targeting gene promoter sequences, particularly how small RNA activates gene transcription, a phenomenon termed RNA activation (RNAa).

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DBCAT (tool)

RRID:SCR_012014

A database of CpG islands and analytical tools for identifying comprehensive methylation profiles in cancer cells.

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MDA-MB-435 (tool)

RRID:CVCL_0417

Cell line MDA-MB-435 is a Cancer cell line with a species of origin Homo sapiens (Human)

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MDA-MB-231 (tool)

RRID:CVCL_0062

Cell line MDA-MB-231 is a Cancer cell line with a species of origin Homo sapiens (Human)

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