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Crosstalk between the activated Slit2-Robo1 pathway and TGF-β1 signalling promotes cardiac fibrosis.

Yunqi Liu | Ziwei Yin | Xueqin Xu | Chen Liu | Xiaoying Duan | Qinlan Song | Ying Tuo | Cuiping Wang | Jing Yang | Shengli Yin
ESC heart failure | 2021

Previous reports indicated that the Slit2-Robo signalling pathway is involved in embryonic heart development and fibrosis in other solid organs, but its function in adult cardiac fibrosis has not been investigated. Here, we investigate the role of the Slit2-Robo1 signalling pathway in cardiac fibrosis.

Pubmed ID: 33236535

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