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Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis.

Daniel B Rosoff | George Davey Smith | Falk W Lohoff
JAMA psychiatry | 2021

Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult.

Pubmed ID: 33175090

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MC_UU_00011/1

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MendelianRandomization (tool)

RRID:SCR_025049

Software Mendelian randomization R package. Encodes several methods for performing Mendelian randomization analyses with summarized data.

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