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Prospective study of gut hormone and metabolic changes after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass.

Rachel Arakawa | Gerardo Febres | Bin Cheng | Abraham Krikhely | Marc Bessler | Judith Korner
PloS one | 2020

Laparoscopic sleeve gastrectomy (SG) has surpassed Roux-en-Y gastric bypass (RYGB) as the most prevalent bariatric procedure worldwide. While RYGB and SG demonstrate equivalent short-term weight loss, long-term weight loss tends to be greater after RYGB. Differences in the effect of these procedures on gastrointestinal hormones that regulate energy homeostasis are felt to partially underlie differences in outcomes. The objective of this study was to prospectively quantify blood levels of gut hormones of energy and glucose homeostasis at one year follow up to delineate possible reasons for greater efficacy of RYGB over SG in achieving weight loss.

Pubmed ID: 32687546

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: T32 DK007559
  • Agency: NCATS NIH HHS, United States
    Id: UL1 TR001873
  • Agency: NCATS NIH HHS, United States
    Id: UL1 TR000040
  • Agency: NIDDK NIH HHS, United States
    Id: T32 DK007271

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