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The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage.

Elissa Tjahjono | Aidan P McAnena | Natalia V Kirienko
BMC biology | 2020

Mitochondrial dysfunction causes or contributes to a wide variety of pathologies, including neurodegenerative diseases, cancer, metabolic diseases, and aging. Cells actively surveil a number of mitochondrial readouts to ensure that cellular homeostasis is maintained.

Pubmed ID: 32600387

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R35 GM129294
  • Agency: Cancer Prevention and Research Institute of Texas, International
    Id: RR150044
  • Agency: Welch Foundation, International
    Id: C-1930

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This is a list of tools and resources that we have found mentioned in this publication.


ggplot2 (tool)

RRID:SCR_014601

Open source software package for statistical programming language R to create plots based on grammar of graphics. Used for data visualization to break up graphs into semantic components such as scales and layers.

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DescTools (tool)

RRID:SCR_027454

Software R package for descriptive statistics and exploratory data analysis. Collection of miscellaneous basic statistic functions and convenience wrappers for efficiently describing data.

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N2_(ancestral) (tool)

RRID:WB-STRAIN:WBStrain00000003

Caenorhabditis elegans with name C. elegans wild type (ancestral). from WB.

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RWPE-1 (tool)

RRID:CVCL_3791

Cell line RWPE-1 is a Transformed cell line with a species of origin Homo sapiens

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