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Bronchoalveolar Lavage-microRNAs Are Potential Novel Biomarkers of Outcome After Lung Transplantation.

Alessandro Palleschi | Gabriella Gaudioso | Valeria Edefonti | Valeria Musso | Andrea Terrasi | Federico Ambrogi | Sara Franzi | Lorenzo Rosso | Paolo Tarsia | Letizia C Morlacchi | Stefano Ferrero | Mario Nosotti | Valentina Vaira
Transplantation direct | 2020

Primary graft dysfunction, infections, and acute rejection (AR) worsen lung transplantation (LTx) outcome and patient survival. Despite significant efforts, reliable biomarkers of acute lung allograft dysfunction are lacking. To address this issue, we profiled the bronchoalveolar lavage (BAL) miRNome in LTx patients.

Pubmed ID: 32548241

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CRAN (tool)

RRID:SCR_003005

Network of ftp and web servers around world that store identical, up to date, versions of code and documentation for R. Package archive network for R programming language.

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Bioconductor (tool)

RRID:SCR_006442

Software repository for R packages related to analysis and comprehension of high throughput genomic data. Uses separate set of commands for installation of packages. Software project based on R programming language that provides tools for analysis and comprehension of high throughput genomic data.

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FactoMineR (tool)

RRID:SCR_014602

Software R package for multivariate analysis which takes into account different types of data structure. Data can be organized in groups of variable, groups of individuals, or into hierarchy of variables.

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MedCalc (tool)

RRID:SCR_015044

Statistical software for ROC curve analysis. MedCalc performs several statistical tests such as method comparison, method evaluation, reference intervals, and meta-analysis.

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ComplexHeatmap (tool)

RRID:SCR_017270

Software package to arrange multiple heatmaps and support various annotation graphics. Used to visualize associations between different sources of data sets and to reveal potential patterns.

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