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Data suggest pharmacological treatment of depression with selective serotonin reuptake inhibitors (SSRI) may impair bone health. Our group has previously modeled compromised craniofacial healing after treatment with sertraline, a commonly prescribed SSRI, and hypothesized potential culprits: alterations in bone cells, collagen, and/or inflammation. Here we interrogate bone lineage cell alterations due to sertraline treatment as a potential cause of the noted compromised bone healing.
Pubmed ID: 32450170
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Cell line MC3T3-E1 is a Spontaneously immortalized cell line with a species of origin Mus musculus
View all literature mentionsCell line RAW 264.7 is a Cancer cell line with a species of origin Mus musculus
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