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How do ethnicity and deprivation impact on life expectancy at birth in people with serious mental illness? Observational study in the UK.

Jayati Das-Munshi | Chin-Kuo Chang | Alex Dregan | Stephani L Hatch | Craig Morgan | Graham Thornicroft | Robert Stewart | Matthew Hotopf
Psychological medicine | 2021

Across international contexts, people with serious mental illnesses (SMI) experience marked reductions in life expectancy at birth. The intersection of ethnicity and social deprivation on life expectancy in SMI is unclear. The aim of this study was to assess the impact of ethnicity and area-level deprivation on life expectancy at birth in SMI, defined as schizophrenia-spectrum disorders, bipolar disorders and depression, using data from London, UK.

Pubmed ID: 32372741

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MC_PC_17214
  • Agency: NIMH NIH HHS, United States
    Id: R01 MH100470
  • Agency: Department of Health, United Kingdom
  • Agency: Medical Research Council, United Kingdom
    Id: MR/S001255/1
  • Agency: Medical Research Council, United Kingdom
    Id: MR/R023697/1

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GATE (tool)

RRID:SCR_002756

Model-based, open source software analysis tool for chromatin states prediction based on time-course epigenetic marks data. It uses a combinatory Finite Mixture model nested with HMM to model the time course marks data in which each single hidden markov model describes the hidden states for a region set across different time points.

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