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Publication

Evolution of Estrogen Receptor Status from Primary Tumors to Metastasis and Serially Collected Circulating Tumor Cells.

Carina Forsare | Pär-Ola Bendahl | Eric Moberg | Charlotte Levin Tykjær Jørgensen | Sara Jansson | Anna-Maria Larsson | Kristina Aaltonen | Lisa Rydén
International journal of molecular sciences | 2020

The estrogen receptor (ER) can change expression between primary tumor (PT) and distant metastasis (DM) in breast cancer. A tissue biopsy reflects a momentary state at one location, whereas circulating tumor cells (CTCs) reflect real-time tumor progression. We evaluated ER-status during tumor progression from PT to DM and CTCs, and related the ER-status of CTCs to prognosis.

Pubmed ID: 32326116

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None found

Associated grants

  • Agency: The Swedish Cancer Society,
    Id: 2016/563; 190388
  • Agency: the Mrs Berta Kamprad Foundation,
    Id: 2017-39
  • Agency: the Crafoord Foundation,
    Id: 20170702
  • Agency: Governmental Funding of Clinical Research within the National Health Service (ALF),
    Id: 2018-40304
  • Agency: the Swedish Research Council,
    Id: 2015-02516
  • Agency: Skåne University Hospital Funds,
    Id: 2017-92502; 2018-92502
  • Agency: the King Gustav V Jubilee Foundation,
    Id: 19/140141
  • Agency: Biocare-strategic research area at Lund University,
    Id: 2016-124359

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MCF-7 (tool)

RRID:CVCL_0031

Cell line MCF-7 is a Cancer cell line with a species of origin Homo sapiens (Human)

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