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Efficacy of biologic therapies for biologic-naïve Japanese patients with moderately to severely active ulcerative colitis: a network meta-analysis.

Toshifumi Hibi | Isao Kamae | Philippe Pinton | Lyann Ursos | Ryuichi Iwakiri | Greg Hather | Haridarshan Patel
Intestinal research | 2021

Several biologic therapies are approved in Japan to treat moderately to severely active ulcerative colitis (UC), but there are no published comparative efficacy studies in a Japanese population. We compared the efficacy of biologics approved in Japan (adalimumab, infliximab, golimumab, and vedolizumab) for treating biologic-naïve patients with UC at their approved doses.

Pubmed ID: 32312035

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Associated grants

  • Agency: Takeda Pharmaceuticals U.S.A.,

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OpenBUGS (tool)

RRID:SCR_024488

Software for analysing complex statistical models using Markov chain Monte Carlo methods.

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