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Evidence gap on antihyperglycemic pharmacotherapy in frail older adults : A systematic review.

Claudia Bollig | Gabriel Torbahn | Jürgen Bauer | Simone Brefka | Dhayana Dallmeier | Michael Denkinger | Annette Eidam | Stefan Klöppel | Andrej Zeyfang | Sebastian Voigt-Radloff | MedQoL-Group (Medication and Quality of Life in frail older persons)
Zeitschrift fur Gerontologie und Geriatrie | 2021

Although antihyperglycemic pharmacotherapy in frail older adults with type 2 diabetes mellitus (T2DM) is challenging, recommendations from international guidelines are mainly based on indirect evidence from trials not including frail participants.

Pubmed ID: 32303827

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PRISMA (tool)

RRID:SCR_018721

Evidence based minimum set of items for reporting in systematic reviews and meta analyses. Focuses on reporting of reviews evaluating randomized trials, but can also be used as basis for reporting systematic reviews of other types of research, particularly evaluations of interventions.

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PROSPERO (tool)

RRID:SCR_019061

International database of prospectively registered systematic reviews in health and social care, welfare, public health, education, crime, justice, and international development, where there is health related outcome. Key features from review protocol are recorded and maintained as permanent record. Aims to provide comprehensive listing of systematic reviews registered at inception to help avoid duplication and reduce opportunity for reporting bias by enabling comparison of completed review with what was planned in protocol.

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