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Conditional immune toxicity rate in patients with metastatic renal and urothelial cancer treated with immune checkpoint inhibitors.

Pier Vitale Nuzzo | Gregory R Pond | Sarah Abou Alaiwi | Amin H Nassar | Ronan Flippot | Catherine Curran | Kerry L Kilbridge | Xiao X Wei | Bradley A McGregor | Toni Choueiri | Lauren C Harshman | Guru Sonpavde
Journal for immunotherapy of cancer | 2020

Immune checkpoint inhibitors (ICIs) are associated with immune-related adverse events (irAEs). Although the incidence and prevalence of irAEs have been well characterized in the literature, less is known about the cumulative incidence rate of irAEs. We studied the cumulative incidence of irAEs, defined as the probability of irAE occurrence over time and the risk factors for irAE development in metastatic urothelial carcinoma (mUC) and renal cell carcinoma (mRCC) patients treated with ICIs.

Pubmed ID: 32234849

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R Project for Statistical Computing (tool)

RRID:SCR_001905

Software environment and programming language for statistical computing and graphics. R is integrated suite of software facilities for data manipulation, calculation and graphical display. Can be extended via packages. Some packages are supplied with the R distribution and more are available through CRAN family.It compiles and runs on wide variety of UNIX platforms, Windows and MacOS.

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