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Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages.

Hai-Ning Wee | Soek-Ying Neo | Deepika Singh | Hui-Chuing Yew | Zhi-Yu Qiu | Xin-Rong Cheryl Tsai | Sin-Yi How | Keng-Yan Caleb Yip | Chay-Hoon Tan | Hwee-Ling Koh
BMC complementary medicine and therapies | 2020

Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in countries such as China, India, Australia and Singapore. Its dried ripe fruits are documented in Traditional Chinese Medicine to treat ailments like rhinitis and dizziness. Its leaves are used traditionally to treat inflammation-related conditions like rheumatic pain.

Pubmed ID: 32188443

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ATCC (tool)

RRID:SCR_001672

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U-937 (tool)

RRID:CVCL_0007

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