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Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity.

Li Ding | Hong-Mei Ning | Pei-Lin Li | Hong-Min Yan | Dong-Mei Han | Xiao-Li Zheng | Jing Liu | Ling Zhu | Mei Xue | Ning Mao | Zi-Kuan Guo | Heng Zhu | Heng-Xiang Wang
Stem cell research & therapy | 2020

Though accumulated evidence has demonstrated visceral organ involvement in acute graft-versus-host disease (aGVHD), how aGVHD influences the bone marrow (BM) niche and the reconstitution of hematopoiesis post-hematopoietic stem cell transplantation remains largely unknown.

Pubmed ID: 32183881

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