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Publication

Hepatitis B Virus-Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma.

Karen Man-Fong Sze | Daniel Wai-Hung Ho | Yung-Tuen Chiu | Yu-Man Tsui | Lo-Kong Chan | Joyce Man-Fong Lee | Kenneth Siu-Ho Chok | Albert Chi-Yan Chan | Chung-Ngai Tang | Victor Wai-Lun Tang | Irene Lai-Oi Lo | Derek Tsz-Wai Yau | Tan-To Cheung | Irene Oi-Lin Ng
Hepatology (Baltimore, Md.) | 2021

Hepatitis B virus (HBV) integrations are common in hepatocellular carcinoma (HCC). In particular, alterations of the telomerase reverse transcriptase (TERT) gene by HBV integrations are frequent; however, the molecular mechanism and functional consequence underlying TERT HBV integration are unclear.

Pubmed ID: 32170761

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Hep-G2 (tool)

RRID:CVCL_0027

Cell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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PLC/PRF/5 (tool)

RRID:CVCL_0485

Cell line PLC/PRF/5 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HeLa (tool)

RRID:CVCL_0030

Cell line HeLa is a Cancer cell line with a species of origin Homo sapiens

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Hep-G2/2.2.15 (tool)

RRID:CVCL_L855

Cell line Hep-G2/2.2.15 is a Cancer cell line with a species of origin Homo sapiens (Human)

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SNU-449 (tool)

RRID:CVCL_0454

Cell line SNU-449 is a Cancer cell line with a species of origin Homo sapiens (Human)

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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