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TRIP6 enhances stemness property of breast cancer cells through activation of Wnt/β-catenin.

Xiaohui Zhao | Chao Jiang | Rui Xu | Qingnan Liu | Guanglin Liu | Yan Zhang
Cancer cell international | 2020

The urgent problem in the treatment of breast cancer is the recurrence induced by breast cancer stem cells (CSCs). Understanding the role and molecular mechanism of specific molecules in breast cancer stem cells can provide a theoretical basis for better treatment. TRIP6 is an adapter protein which belongs to the zyxin family of LIM proteins and is important in regulating the functions of CSCs. The present study aims to investigate the effects and mechanism of TRIP6 in breast cancer.

Pubmed ID: 32082081

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