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C-reactive protein as a potential biomarker for disease progression in dengue: a multi-country observational study.

Nguyen Lam Vuong | Huynh Thi Le Duyen | Phung Khanh Lam | Dong Thi Hoai Tam | Nguyen Van Vinh Chau | Nguyen Van Kinh | Ngoun Chanpheaktra | Lucy Chai See Lum | Ernesto Pleités | Nick Keith Jones | Cameron Paul Simmons | Kerstin Rosenberger | Thomas Jaenisch | Christine Halleux | Piero Luigi Olliaro | Bridget Wills | Sophie Yacoub
BMC medicine | 2020

Dengue infection can cause a wide spectrum of clinical outcomes. The severe clinical manifestations occur sufficiently late in the disease course, during day 4-6 of illness, to allow a window of opportunity for risk stratification. Markers of inflammation may be useful biomarkers. We investigated the value of C-reactive protein (CRP) measured early on illness days 1-3 to predict dengue disease outcome and the difference in CRP levels between dengue and other febrile illnesses (OFI).

Pubmed ID: 32063229

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Associated grants

  • Agency: World Health Organization, International
    Id: 001
  • Agency: European Union, International
    Id: FP7-281803 IDAMS
  • Agency: World Health Organization, International
    Id: UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases

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