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Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.

Bin Wu | Qingen Song | Yongkang Zhang | Changshui Wang | Mengqi Yang | Jun Zhang | Wenxiu Han | Pei Jiang
Lipids in health and disease | 2020

Menopause predisposes individuals to affective disorders, such as depression, which is tightly related to neuroinflammation. While the neuroinflammatory condition has been demonstrated in ovariectomized (OVX) rodents, there is limited evidence concerning microglial polarization, a key process in brain immune activation, in menopause-related brain.

Pubmed ID: 31915015

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Thermo Fisher Scientific (tool)

RRID:SCR_008452

Commercial vendor and service provider of laboratory reagents and antibodies. Supplier of scientific instrumentation, reagents and consumables, and software services.

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Proteintech Group (tool)

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Abcam (tool)

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SD (tool)

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Rattus norvegicus with name SD from RGD.

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