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Antibody-Dependent Natural Killer Cell Activation After Ebola Vaccination.

Helen R Wagstaffe | Elizabeth A Clutterbuck | Viki Bockstal | Jeroen N Stoop | Kerstin Luhn | Macaya Douoguih | Georgi Shukarev | Matthew D Snape | Andrew J Pollard | Eleanor M Riley | Martin R Goodier
The Journal of infectious diseases | 2021

Antibody Fc-mediated functions, such as antibody-dependent cellular cytotoxicity, contribute to vaccine-induced protection against viral infections. Fc-mediated function of anti-Ebola glycoprotein (GP) antibodies suggest that Fc-dependent activation of effector cells, including natural killer (NK) cells, could play a role in vaccination against Ebola virus disease.

Pubmed ID: 31821493

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: G1000808

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BD FACSDiva Software (tool)

RRID:SCR_001456

A collection of tools for flow cytometer and application setup, data acquisition, and data analysis that help streamline flow cytometry workflows. It provides features to help users integrate flow systems into new application areas, including index sorting for stem cell and single-cell applications, as well as automation protocols for high-throughput and robotic laboratories.

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