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Alterations in Cortical Thickness in Young Male Patients With Childhood-Onset Adult Growth Hormone Deficiency: A Morphometric MRI Study.

Hongbo Yang | Kang Li | Xinyu Liang | Bin Gu | Linjie Wang | Gaolang Gong | Feng Feng | Hui You | Bo Hou | Fengying Gong | Huijuan Zhu | Hui Pan
Frontiers in neuroscience | 2019

The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis plays an important role in brain structure and maintenance of brain function. There is a close correlation between serum GH and IGF1 levels and age-related cognitive function. The effects of childhood-onset growth hormone deficiency (GHD)on brain morphology are underestimated so far.

Pubmed ID: 31695595

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SurfStat (tool)

RRID:SCR_007081

A Matlab toolbox for the statistical analysis of univariate and multivariate surface data using linear mixed effects models and random field theory.

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