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Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor.

Qian-Qian Chen | Jia-Min Shi | Zhou Ding | Qing Xia | Tian-Sheng Zheng | Yan-Bei Ren | Ming Li | Li-Hong Fan
Cancer management and research | 2019

Berberine (BBR) from the widely used Chinese herbal medicine Huanglian has an array of pharmacological and biochemical properties, including anti-neoplastic activity. However, the specific mechanisms underlying these properties are unknown. The aim of this study was to explore the anti-tumor mechanisms of BBR in non-small cell lung cancer (NSCLC).

Pubmed ID: 31695492

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miRBase (tool)

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Central online repository for microRNA nomenclature, sequence data, annotation and target prediction.Collection of published miRNA sequences and annotation.

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