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High expression of HSP90 is associated with poor prognosis in patients with colorectal cancer.

Shuming Zhang | Shichao Guo | Zhangfu Li | Dan Li | Qimin Zhan
PeerJ | 2019

Heat shock protein 90 (HSP90) is a highly conserved chaperone with an approximate molecular weight of 90-kDa. It plays a critical role in maintaining stability and homeostasis of oncoproteins, helping cancer cells living in the unsuitable environmental conditions. The current study aims to inquire the difference of HSP90 expression in tumor tissues and normal tissues, analyze the correlation between HSP90 expression and the prognoses of patients with colorectal cancer (CRC), and investigate its role in CRC preliminarily.

Pubmed ID: 31687275

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