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Implementation of Case-Based Surveillance and Real-time Polymerase Chain Reaction to Monitor Bacterial Meningitis Pathogens in Chad.

Marietou F Paye | Kadidja Gamougame | Sarah K Payamps | Alicia R Feagins | Daugla Doumagoum Moto | Ronelngar Moyengar | Nathan Naïbeï | Jeni Vuong | Alpha Oumar Diallo | Ashley Tate | Heidi M Soeters | Xin Wang | Mahamat Ali Acyl
The Journal of infectious diseases | 2019

Meningococcal serogroup A conjugate vaccine (MACV) was introduced in Chad during 2011-2012. Meningitis surveillance has been conducted nationwide since 2003, with case-based surveillance (CBS) in select districts from 2012. In 2016, the MenAfriNet consortium supported Chad to implement CBS in 4 additional districts and real-time polymerase chain reaction (rt-PCR) at the national reference laboratory (NRL) to improve pathogen detection. We describe analysis of bacterial meningitis cases during 3 periods: pre-MACV (2010-2012), pre-MenAfriNet (2013-2015), and post-MenAfriNet (2016-2018).

Pubmed ID: 31671450

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