Searching the Resource Information Network
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
This article contains raw and processed data related to research published by Takiya et al. [1]. Literature have shown that treatment with the nonsteroidal anti-inflammatory agent sodium salicylate (SS) during the first days postpartum in dairy cows increased lactation performance [2], and tended to alter glucose metabolism [3]. Yet, the specific effects of systemic SS treatment on the proteome of the adipose tissue (AT) and on the inflammatory process in AT of postpartum cows is unknown. Subcutaneous AT samples were collected at 7 d of lactation from control cows (n = 5) and from cows treated with 2.3 g/L SS (n = 5) via drinking water during the first 7 d of lactation. Protein extraction and liquid chromatography-mass spectrometry were performed to obtain proteomics data. Differential abundance of proteins was determined through MS1 intensity based label-free method. Proteomics analysis generated a novel dataset consisted of 1422 proteins, 80 (5.6%) of which were differentially abundant [fold change ± 1.5, P < 0.05 2-way ANOVA] when comparing control and SS-treated cows. The present dataset of subcutaneous AT proteome from postpartum dairy cows treated with SS can be used as a reference for any research involving nonsteroidal anti-inflammatory agent treatment in dairy cows or in comparative research between species.
Pubmed ID: 31667314
Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.
Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB.
View all literature mentionsCentral repository for collection of functional information on proteins, with accurate and consistent annotation. In addition to capturing core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and experimental and computational data. The UniProt Knowledgebase consists of two sections, UniProtKB/Swiss-Prot and UniProtKB/TrEMBL. UniProtKB/Swiss-Prot (reviewed) is a high quality manually annotated and non-redundant protein sequence database which brings together experimental results, computed features, and scientific conclusions. UniProtKB/TrEMBL (unreviewed) contains protein sequences associated with computationally generated annotation and large-scale functional characterization that await full manual annotation. Users may browse by taxonomy, keyword, gene ontology, enzyme class or pathway.
View all literature mentions