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Publication

Magnetic resonance spectroscopy evidence for declining gliosis in MS patients treated with ocrelizumab versus interferon beta-1a.

Erin L MacMillan | Julia J Schubert | Irene M Vavasour | Roger Tam | Alexander Rauscher | Carolyn Taylor | Rick White | Hideki Garren | David Clayton | Victoria Levesque | David Kb Li | Shannon H Kolind | Anthony L Traboulsee
Multiple sclerosis journal - experimental, translational and clinical | 2019

Magnetic resonance spectroscopy quantitatively monitors biomarkers of neuron-myelin coupling (N-acetylaspartate (NAA)), and inflammation (total creatine (tCr), total choline (tCho), myo-inositol (mI)) in the brain.

Pubmed ID: 31662881

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LCModel (tool)

RRID:SCR_014455

Software for automatic quantification of in vivo proton MR spectra. Though it is mainly used for brain analysis, it can be used for a variety of analyses in different areas of the body. It receives time-domain data as input and gives a one page summary output. It is fully automatic, non-interactive, and operator-independent.

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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