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A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol.

Caroline Wright | Simon P Hart | Victoria Allgar | Anne English | Flavia Swan | Judith Dyson | Gerry Richardson | Maureen Twiddy | Judith Cohen | Jamilla Hussain | Miriam Johnson | Ian Hargreaves | Michael G Crooks
ERJ open research | 2019

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease that causes breathlessness and cough that worsen over time, limiting daily activities and negatively impacting quality of life. Although treatments are now available that slow the rate of lung function decline, trials of these treatments have failed to show improvement in symptoms or quality of life. There is an immediate unmet need for evidenced-based interventions that improve patients' symptom burden and make a difference to everyday living. This study aims to assess the feasibility of conducting a definitive randomised controlled trial of a holistic, complex breathlessness intervention in people with IPF.

Pubmed ID: 31649946

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Associated grants

  • Agency: Department of Health, United Kingdom
    Id: PB-PG-1216-20020

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RRID:SCR_006087

A primary clinical trial registry which houses proposed, ongoing, and completed clinical research studies. An ISRCTN is a simple numeric system for the unique identification of randomized controlled trials worldwide. The registry provides content validation and curation and the unique identification number necessary for publication. Submitted studies range from cancer to urological diseases.

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