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Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns.

Hira Hasan | Sin-Hee Park | Cyril Auger | Eugenia Belcastro | Kensuke Matsushita | Benjamin Marchandot | Hyun-Ho Lee | Abdul Wahid Qureshi | Gilles Kauffenstein | Patrick Ohlmann | Valérie B Schini-Kerth | Laurence Jesel | Olivier Morel
Journal of clinical medicine | 2019

Besides its well-known functions in hemostasis, thrombin plays a role in various non-hemostatic biological and pathophysiologic processes. We examined the potential of thrombin to promote premature atrial endothelial cells (ECs) senescence.

Pubmed ID: 31581517

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