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Cacao extract enriched in polyphenols prevents endocrine-metabolic disturbances in a rat model of prediabetes triggered by a sucrose rich diet.

María Cecilia Castro | Hernán Villagarcía | Ada Nazar | Luisa González Arbeláez | María Laura Massa | Héctor Del Zotto | José Luis Ríos | Guillermo R Schinella | Flavio Francini
Journal of ethnopharmacology | 2020

Cocoa extracts rich in polyphenols are used as potential agent for treating diabetes. Cocoa polyphenols have been proved to ameliorate important hallmarks of type-2 diabetes (T2D). They can regulate glucose levels by increasing insulin secretion, promoting β-cell proliferation and a reduction of insulin resistance. In addition, epidemiological evidence indicates that consumption of flavonoid decreases the incidence of T2D.

Pubmed ID: 31580944

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WI (tool)

RRID:RGD_13508588

Rattus norvegicus with name WI from RGD.

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