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Repeated intravenous administration of silica nanoparticles induces pulmonary inflammation and collagen accumulation via JAK2/STAT3 and TGF-β/Smad3 pathways in vivo.

Yang Yu | Tingting Zhu | Yang Li | Li Jing | Man Yang | Yanbo Li | Junchao Duan | Zhiwei Sun
International journal of nanomedicine | 2019

The health hazards of silica nanoparticle (SiNP) are raising worldwide concern as SiNPs has become the second largest manufactured nanomaterial in global markets. However, insufficient data for the adverse health effects and safety evaluation of SiNPs are remaining a big question.

Pubmed ID: 31564876

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Cell Signaling Technology (tool)

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