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Publication

CHI3L1 promotes proliferation and improves sensitivity to cetuximab in colon cancer cells by down-regulating p53.

Kaitai Liu | Ming Jin | Shuang Ye | Senxiang Yan
Journal of clinical laboratory analysis | 2020

Chitinase 3-like protein 1 (CHI3L1) is most likely a malignant tumor metastasis-associated gene. However, the functions of CHI3L1 in colon cancer cell proliferation and its cetuximab sensitivity are still unclear. We aimed to investigate the mechanism of CHI3L1 in promoting colon cancer cell proliferation and its sensitivity to cetuximab.

Pubmed ID: 31536166

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Associated grants

  • Agency: Medical Technology Project of Ningbo,
    Id: 2018A01

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

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HEK293T (tool)

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HCT 116 (tool)

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SW620 (tool)

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